Glossary Term
Diluent
Any liquid or solid material used to lessen the strength or flavor of a solution or mixture of another ingredient.
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Glossary Term
Any liquid or solid material used to lessen the strength or flavor of a solution or mixture of another ingredient.
Glossary Term
To reduce in strength or concentration, especially by the addition of water.
Glossary Term
Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis.
Glossary Term
Any method that extracts and purifies DNA from biological samples, which can include the proper handling of biological samples prior to nucleic acid isolation, the separation of DNA from the rest of the components in the samples, and the storage of the DNA isolates.
Glossary Term
A family of enzymes that catalyze the formation of phosphodiester bonds to repair broken strands of DNA.
Glossary Term
Enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage.
Glossary Term
An RNA complex consisting of two complementary base-paired strands of RNA.
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The largest difference between, or ratio of, an instrument's or method's highest and lowest value in a set, such as pixel (voxel) values in an image.
Glossary Term
A 50-150bp DNA sequence that increases the rate of transcription of coding sequences. It may be located at various distances and in either orientation upstream from, downstream from or within a structural gene. When bound by a specific transcription factor it increases the levels of expression of the gene, but is not sufficient alone to cause expression. Distinguished from a promoter, that is alone sufficient to cause expression of the gene when bound.
Glossary Term
Changes in the regulation of the expression of gene activity without alteration of genetic structure.
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The complete set of epigenetic modifications on the genome of a cell.
Glossary Term
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.