Glossary Term
DNA Repair
PCR TermsEN
Definition
Enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16513. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
DNA Damage RepairDNA RepairUnscheduled DNA Synthesis
References
- NCI Thesaurus 26.09d — DNA Repair (C16513)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16513. NCI definition, reproduced without modification under CC BY 4.0.
- PSF3 recruits Polθ to stalled replication forks to promote DNA repair. — Proc Natl Acad Sci U S A, 2026-10-20 (PMID 42900728; literature)
- TONSL/TONSOKU binding to histone H3.1 is required for DNA repair. — Sci Adv, 2026-10-16 (PMID 42886812; literature)
- FAT1 generates a nuclear fragment that impairs DNA damage repair in gastric cancer. — J Biol Chem, 2026-10-22 (PMID 42914025; literature)
- LncRNA MIR4435-2HG confers radioresistance in NSCLC by sponging miR-1-3p to upregulate DNA-PKcs and selectively promote NHEJ repair. — Cell Signal, 2026-10-22 (PMID 42913901; literature)
- PSMB7 is associated with DNA damage repair and immune microenvironment features and serves as a prognostic biomarker. — Mol Biol Rep, 2026-10-25 (PMID 42927543; literature)
- ERG inhibition selectively sensitizes ERG-positive prostate cancer to radiation through DNA repair vulnerabilities and enhances response to androgen receptor inhibitors. — J Exp Clin Cancer Res, 2026-10-23 (PMID 42926195; literature)
- Removal of VirD2 from a synthetic T-DNA complex of Agrobacterium by the host DNA repair protein TDP2. — PLoS Pathog, 2026-10-26 (PMID 42932378; literature)
- PARP1 directly disassembles nucleosomes to regulate DNA repair. — Mol Cell, 2026-10-23 (PMID 42914980; literature)
- Tubulin acetylation regulates nuclear shape fluctuations and DNA repair. — Nat Cell Biol, 2026-10-28 (PMID 42951908; literature)
- Joint Effects of ALDH2 rs671 and Pathogenic Germline Variants in DNA Repair Genes on Risk of Aerodigestive and Gastrointestinal Cancers. — Cancer Epidemiol Biomarkers Prev, 2026-10-27 (PMID 42944724; literature)