Glossary Term
Epitope
PCR TermsEN
Definition
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C13189. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Antigenic DeterminantAntigenic DeterminantsBinding DeterminantsEpitope
References
- NCI Thesaurus 26.09d — Epitope (C13189)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C13189. NCI definition, reproduced without modification under CC BY 4.0.
- A novel dual-epitope ELISA reveals heterogeneity of circulating lipoprotein lipase: distinguishing intact LPL from total LPL. — Clin Chim Acta, 2026-10-18 (PMID 42893715; literature)
- Development of a chimeric multi-epitope vaccine targeting surface-exposed proteins of Chlamydia psittaci through immunoinformatics and structural vaccinology. — Hum Immunol, 2026-10-15 (PMID 42879944; literature)
- Epitope-diverse autoantibodies induce neutrophil-epithelial niches driving kidney injury in ANCA-associated glomerulonephritis. — J Exp Med, 2026-10-19 (PMID 42895484; literature)
- HLA-driven variability in human cytomegalovirus immune recognition: Epitope predictions from a kidney transplant Cohort. — PLoS One, 2026-10-15 (PMID 42879396; literature)
- In silico multi-epitope vaccine design against Irkut virus using immunoinformatic and reverse vaccinology. — Virus Genes, 2026-10-22 (PMID 42918948; literature)
- Adjuvant selection and optimization in the design of an epstein-barr virus-based multi-epitope vaccine against Burkitt lymphoma. — J Egypt Natl Canc Inst, 2026-10-27 (PMID 42934362; literature)
- Divergent Functional Checkpoints Determine Epitope-Specific ADE Outcomes of SARS-CoV-2 Entry. — Antiviral Res, 2026-10-26 (PMID 42933540; literature)