Glossary Term
Epigenome
Definition
The complete set of epigenetic modifications on the genome of a cell.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C153195. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
References
- NCI Thesaurus 26.09d — Epigenome (C153195)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C153195. NCI definition, reproduced without modification under CC BY 4.0.
- From iPSC Disease Modeling to Epigenome Editing: Toward Therapeutic Reversal of Genomic Imprinting Disorders. — Neurosci Res, 2026-10-09 (PMID 42854759; literature)
- The Autophagy-Epigenome Axis in Hypothalamic Neurons: A Unified Framework for Understanding Obesity Persistence and Therapeutic Resistance. — Exp Clin Endocrinol Diabetes, 2026-10-05 (PMID 42833273; literature)
- Epigenome-Wide Association Study of Abdominal Aortic Aneurysm Identifies Central Role for Inflammatory Pathways. — Circulation, 2026-09-29 (PMID 42808173; literature)
- A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease. — Nat Aging, 2026-09-24 (PMID 42786309; literature)
- Ryder: Epigenome normalization using a two-tier model and internal reference regions. — Bioinformatics, 2026-10-15 (PMID 42878397; literature)
- Dynamics and inheritance of the paternal epigenome. — Curr Opin Plant Biol, 2026-10-14 (PMID 42874416; literature)
- Autoimmunity induced by epigenome alteration affecting thymic Treg cell development. — Proc Natl Acad Sci U S A, 2026-10-14 (PMID 42873787; literature)
- Baseline blood-based DNA methylation in impaired fasting glucose and impaired glucose tolerance: epigenome-wide differences and associations with subsequent progression to type 2 diabetes mellitus. — Diabetes Res Clin Pract, 2026-10-13 (PMID 42869252; literature)
- The mitochondrial epigenome and noncoding genome in aging and brain diseases. — Trends Neurosci, 2026-10-10 (PMID 42859082; literature)
- Preconception paternal PFAS exposure in mice reprograms the placental epigenome. — Mol Hum Reprod, 2026-10-24 (PMID 42921749; literature)
- A droplet-based long-read single-cell epigenome sequencing method for the high-throughput profiling of multidimensional regulatory elements within individual cells. — Cell Discov, 2026-10-27 (PMID 42934226; literature)
- The Gut Microbiota-Epigenome Axis in Bariatric Surgery: Mechanistic Insights and Therapeutic Perspectives. — Metabolites, 2026-10-09 (PMID 42941230; literature)
