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Glossary Term
The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.
Article
Research record from Diagn Pathol, 2026-04-21. PMID 42010682.
Article
Research record from Cancer Manag Res, 2026-03-17. PMID 41869573.
Glossary Term
Genomic instability associated with the presence of hypermutability in specific genetic marker regions resulting from defective DNA mismatch repair.
Indicators
This gene plays a role in DNA mismatch repair.
Indicators
This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1.
Indicators
This gene is involved in mismatch repair and plays a role in several cancers.
Tests
The determination of the amount of MLH3 mismatch repair protein in a biological sample.
Tests
The determination of the amount of MSH3 mismatch repair protein in a biological sample.
Indicators
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 3.
Indicators
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
Tests
The determination of the number of mismatch between the study subject and his or her donor for the human leukocyte antigen, class I, group A (HLA-A).
