Indicator Explainer
PMS2 Gene
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C18591. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — PMS2 Gene (C18591)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C18591. NCI definition, reproduced without modification under CC BY 4.0.
- An Integrated Clinical, Germline, Somatic, and In Silico Approach to Assess a Novel PMS2 Gene Variant Identified in Two Unrelated Lynch Syndrome Families. — Cancers (Basel), 2025-07-11 (PMID 40723192; literature)
- In silico splicing analysis of the PMS2 gene: exploring alternative molecular mechanisms in PMS2-associated Lynch syndrome. — BMC Genom Data, 2024-11-27 (PMID 39592919; literature)