Article
Nirmatrelvir/Ritonavir and Subsequent PCR Negativity in Patients With B-Cell Lymphoma and Prolonged SARS-CoV-2 PCR Positivity: A Case Series.
Research record from EJHaem, 2026-10-24. PMID 42927348.
Loading
Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Article
Research record from EJHaem, 2026-10-24. PMID 42927348.
Glossary Term
A reaction that contains all reagents except sample nucleic acid. Amplification in the NTC signals contamination of reagents or the environment, so NTC behavior is one of the first run-validity checks in any qPCR run log.
Article
Research record from Front Med (Lausanne), 2026-03-30. PMID 41982550.
Glossary Term
A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein.
Article
Research record from JMIR Res Protoc, 2026-07-10. PMID 42430219.
Glossary Term
Any of various amplification and detection strategies applied to detection of virus contamination in donor blood. Specifically designed to detect recently infected individuals during the latency period before seroconversion.
Glossary Term
The sample-preparation stage that lyses cells or virions and purifies DNA/RNA before amplification. Extraction quality (yield, purity, inhibitors removed) often limits assay performance more than the PCR itself, and it defines required instruments and hands-on time in a workflow.
Glossary Term
Laboratory procedure in which single stranded nucleic acids are allowed to interact so that complexes, or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. (From Biology-online)
Glossary Term
A subunit of DNA or RNA consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA and ribose in RNA).
Glossary Term
Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription. NER is targeted to actively transcribed regions of the genome. During NER in eukaryotes, shape irregularities are detected by protein complexes that slide along the DNA molecule and induce cuts on each side of a lesion several nucleotides away. Removal of the damaged 25-30 nucleotide fragment is followed by repair synthesis and ligation.
Glossary Term
A DNA polymer made up of a small number of nucleotides.
Glossary Term
Short DNA oligonucleotide chains used to prime DNA (and in some cases RNA) synthesis.