Glossary Term

Nonsense Mutation

PCR TermsEN

Definition

A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein.

Extended Notes

Source: National Cancer Institute, NCI Thesaurus 26.09d, C62198. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.

Also Known As

Nonsense MutationPremature Termination AbnormalityPremature Termination MutationStop Gain

References

NCI Thesaurus 26.09d — Nonsense Mutation (C62198)
Source: National Cancer Institute, NCI Thesaurus 26.09d, C62198. NCI definition, reproduced without modification under CC BY 4.0.