Glossary Term
Oligonucleotide
PCR TermsEN
Definition
A DNA polymer made up of a small number of nucleotides.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C713. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
OligoOligonucleotide
References
- NCI Thesaurus 26.09d — Oligonucleotide (C713)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C713. NCI definition, reproduced without modification under CC BY 4.0.
- Nonclinical Development of Oligonucleotide-Based Therapeutics: Insights from an IQ DruSafe ONT Working Group Survey. — Nucleic Acid Ther, 2026-10-08 (PMID 42845133; literature)
- Delivery architectures for oligonucleotide therapeutics in genetic and rare diseases: GalNAc-based hepatocyte targeting and extrahepatic translation. — J Control Release, 2026-10-03 (PMID 42829049; literature)
- On-support phosphitylation for oligonucleotide modification. — Nat Chem, 2026-10-01 (PMID 42509394; literature)
- Phospholipase Fluorogenic Probes and Molecular Determinants of Cyclic Guanosine Monophosphate-Adenosine Monophosphate Binding to Cyclic Oligonucleotide-Based Antiphage Signaling System CapV. — ACS Chem Biol, 2026-10-15 (PMID 42875168; literature)
- Enhanced electrochemically-directed oligonucleotide synthesis via porous silica thin-film for DNA data storage. — Microsyst Nanoeng, 2026-10-12 (PMID 42864311; literature)
- An Easy Oligonucleotide Platform for Rapid, Post-Isolation EV Modification: Dual-Function Uptake Control and Enhanced Targeting. — ACS Appl Bio Mater, 2026-10-19 (PMID 42895173; literature)
- Prostate Cancer Patient-Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)-Based Personalized Therapy. — Adv Healthc Mater, 2026-10-11 (PMID 42860576; literature)
- Parallel hierarchical gene assembly from oligonucleotide pools on an integrated digital microfluidic platform. — Lab Chip, 2026-10-27 (PMID 42741960; literature)
- Considerations of Gene Expression Analysis Methods for Gapmer Antisense Oligonucleotide-Treated Samples. — Nucleic Acid Ther, 2026-10-25 (PMID 42928554; literature)