Glossary Term
Nucleic Acid Extraction
Extraction MethodologyEN
Definition
The sample-preparation stage that lyses cells or virions and purifies DNA/RNA before amplification. Extraction quality (yield, purity, inhibitors removed) often limits assay performance more than the PCR itself, and it defines required instruments and hands-on time in a workflow.
Related Terms
References
- A PfAgo-assisted artificial nucleic acid circuit for extraction-free and ultrasensitive detection of Staphylococcus aureus in dairy products. — Biosens Bioelectron, 2026-10-07 (PMID 42854435; literature)
- Standardized Workflow for Human Fecal Sample Collection and Automated Deoxyribonucleic Acid Extraction Using a Magnetic Particle Processor. — J Vis Exp, 2026-09-11 (PMID 42730659; literature)
- Finger-actuated microfluidic device for point-of-care circulating cell-free nucleic acid extraction. — Lab Chip, 2026-08-21 (PMID 42627029; literature)
- Microfluidic integrated nucleic acid test (MINT) enabled by coupling FEN1-aided RPA with wax-purification and bead-carrier. — Talanta, 2026-10-19 (PMID 42901063; literature)