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A measurement of the length of time that it takes for clotting to occur when activating reagents are added to a plasma specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.
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Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid. Growth factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tissue is higher than that of normal tissue.
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Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation through the mediation of proteolysis that converts factor X into an active protease.
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Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade.
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Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.
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Coagulation factor X (488 aa, ~55 kDa) is encoded by the human F10 gene. This protein is involved in proteolysis and blood coagulation.
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Coagulation factor XI (625 aa, ~70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX.
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Coagulation factor XII (615 aa, ~68 kDa) is encoded by the human F12 gene. This protein is involved in blood coagulation and fibrinolysis.
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This gene plays an inhibitory role in cell survival and proliferation.
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This gene is involved in the epidermal growth factor signal transduction pathway.
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This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.
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Erythropoietin (193 aa, ~21 kDa) is encoded by the human EPO gene. This protein plays a role in both erythropoiesis and the maintenance of red blood cell volume.