Indicator Explainer
Coagulation Factor IX
Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation through the mediation of proteolysis that converts factor X into an active protease.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C28482. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Coagulation Factor IX (C28482)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C28482. NCI definition, reproduced without modification under CC BY 4.0.
- Substitution-induced allosteric activation of coagulation factor IX as a potential alternative hemophilia A treatment strategy. — Thromb Res, 2026-08-14 (PMID 42617289; literature)
- Immunopeptidomics of blood coagulation factor IX: a core peptide derived from the protease domain is promiscuously presented on HLA-DR. — Res Pract Thromb Haemost, 2026-05-01 (PMID 42433597; literature)
- Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy. — Blood, 2026-01-01 (PMID 41198051; literature)