Indicator Explainer
Coagulation Factor VII
Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16570. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
Related Tests
Tests that measure or involve this indicator.
References
- NCI Thesaurus 26.09d — Coagulation Factor VII (C16570)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16570. NCI definition, reproduced without modification under CC BY 4.0.
- Compound heterozygous variants in F7 gene causing severe factor VII deficiency without bleeding: A genotypic and laboratory analysis. — Blood Cells Mol Dis, 2026-06-22 (PMID 42361596; literature)
- Identification of berbamine hydrochloride as a novel coagulation factor VII inhibitor by natural product library screening using zebrafish as a model. — Sci Rep, 2026-02-20 (PMID 41720986; literature)
- Coagulation Factor VII Deficiency: A Review of the Clinical Implications and Approaches to Replacement Therapy and Prophylaxis. — Pediatr Blood Cancer, 2025-06-26 (PMID 40571675; literature)
- [The Effect of p.Thr241Asn and p.Cys389Gly Mutations on Coagulation Factor VII Structure and Function]. — Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2025-06-01 (PMID 40613181; literature)
- A Family With Factor VII Deficiency: A Possible Autosomal Dominant Transmission. — Cureus, 2025-04-18 (PMID 40385775; literature)
- Analysis of clinical manifestations and molecular pathogenesis of six patients with hereditary blood coagulation factor VII deficiency. — Thromb Res, 2025-03-13 (PMID 40117674; literature)