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Erythropoietin
Erythropoietin (193 aa, ~21 kDa) is encoded by the human EPO gene. This protein plays a role in both erythropoiesis and the maintenance of red blood cell volume.
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Indicators
Erythropoietin (193 aa, ~21 kDa) is encoded by the human EPO gene. This protein plays a role in both erythropoiesis and the maintenance of red blood cell volume.
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The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.
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A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
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This gene plays a role in the regulation of both DNA repair and protein localization.
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This gene is involved in the mediation of protein ubiquitination.
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Fatty acid-binding protein, heart (133 aa, ~15 kDa) is encoded by the human FABP3 gene. This protein plays a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
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This gene is involved in ubiquitin-dependent proteolysis and regulation of the G1-S cell cycle checkpoint.
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The body’s iron-storage protein measurable in serum — the most informative single test of iron stores.
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A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation.
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Fibroblast growth factor 23 (251 aa, ~28 kDa) is encoded by the human FGF23 gene. This protein is involved in inhibition of renal tubular phosphate transport.
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A heterodimeric glycoprotein hormone secreted by the gonadotropic cells of the anterior pituitary gland. This hormone is involved in gonadal development, growth, maturation and reproductive processes, including the regulation of spermatogenesis in males and follicular growth and ovulation in females.
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Galectin-3 (250 aa, ~26 kDa) is encoded by the human LGALS3 gene. This protein plays a role in both antibody-mediated immunity and carbohydrate binding.