Indicator Explainer
Galectin-3
Galectin-3 (250 aa, ~26 kDa) is encoded by the human LGALS3 gene. This protein plays a role in both antibody-mediated immunity and carbohydrate binding.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C104859. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Galectin-3 (C104859)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C104859. NCI definition, reproduced without modification under CC BY 4.0.
- Methodological considerations in interpreting serum galectin-3 as a predictor of incident type 2 diabetes. — J Diabetes Investig, 2026-10-17 (PMID 42888924; literature)
- Galectin-3 accelerates the progression of cerebral infarction by regulating the ERK/ROS/BRD4-mediated P2X7R/MerTK balance in microglia. — Biochem Biophys Res Commun, 2026-10-08 (PMID 42868724; literature)
- Berbamine hydrochloride as a brain-penetrant galectin-3 inhibitor in a model of Huntington's disease. — Brain, 2026-10-01 (PMID 41772384; literature)
- Serum Galectin-3 in Diabetic Foot Infections: A Case-Control Evaluation of Its Diagnostic and Severity-Grading Utility. — Infect Dis Clin Microbiol, 2026-09-30 (PMID 42861337; literature)