Indicator Explainer
Fibroblast Growth Factor 23
Fibroblast growth factor 23 (251 aa, ~28 kDa) is encoded by the human FGF23 gene. This protein is involved in inhibition of renal tubular phosphate transport.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C104384. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Fibroblast Growth Factor 23 (C104384)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C104384. NCI definition, reproduced without modification under CC BY 4.0.
- Clinical Significance of Klotho, Fibroblast Growth Factor 23, and their Ratio for Acute Kidney Injury in Sepsis Patients. — Med Princ Pract, 2026-10-09 (PMID 42853715; literature)
- The Binding of Fibroblast Growth Factor 23 (FGF23) to FGF Receptor-αKlotho Complex Increases Sinoatrial Electrical Activity. — Acta Physiol (Oxf), 2026-10-01 (PMID 42677728; literature)
- Changes of serum fibroblast growth factor 23 (FGF23) and Klotho in diabetic kidney disease and their correlation with coronary artery calcification: a retrospective study. — Arch Endocrinol Metab, 2026-10-20 (PMID 42905600; literature)
- Elevated circulating fibroblast growth factor 23 is associated with acute kidney injury and mortality in coronavirus disease 2019 (COVID-19). — J Bras Nefrol, 2026-10-01 (PMID 42641144; literature)