Glossary Term
DNA Ligase
A family of enzymes that catalyze the formation of phosphodiester bonds to repair broken strands of DNA.
Loading
Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Glossary Term
A family of enzymes that catalyze the formation of phosphodiester bonds to repair broken strands of DNA.
Glossary Term
An Exonuclease is a hydrolase (nuclease) that specifically catalyzes the hydrolysis of terminal phosphodiester bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
Glossary Term
Fluorescence is a luminescence (i.e., optical phenomenon) in cold bodies, in which a molecule absorbs a high-energy photon, and re-emits it as a lower-energy (longer-wavelength) photon. The energy difference between the absorbed and emitted photons ends up as molecular vibrations (heat).
Glossary Term
A class of dyes when excited by light of certain wavelengths, emit photons and become fluorescent. Fluorescence gives fluorochromes imaging characteristics and are used to label or stain biological structures.
Glossary Term
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by forming a phosphodiester bond.
Glossary Term
Any physical object that is useful for prevention, diagnosis, monitoring, or treatment of disease or other conditions.
Glossary Term
Metabolomics is the study of the biological metabolic profile of a cellular specimen in a specific environment at an isolated timepoint. This discipline depicts the physiological states of cells and organisms by focusing on carbohydrates, lipids, and other metabolites. Several analytical techniques are utilized to quantify the metabolic content of specimens such as mass spectrometry and electrophoretic applications.
Glossary Term
A subunit of DNA or RNA consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA and ribose in RNA).
Glossary Term
A measure of the probability that a result happened by chance. The lower the p-value, the more likely it is that the result was caused by phenomenon of interest.
Glossary Term
The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation.
Glossary Term
Chemicals that are added to drug products to prolong shelf life and maintain sterility. Protection of formulations, especially aqueous solutions, against microbial growth requires use of either antibacterial or antifungal preservatives. Generally, such agents are active against either bacteria or fungi but a few are active against both. The antimicrobials include but not limited to chlorobutanol, benzyl alcohol, sodium benzoate, sorbic acid, and phenol. The antioxidizing agents include butylated hydroxytoluene, hydroxyanisole, propyl gallate, and sulfites. The necessary addition of preservatives for both safety and economy sometimes has been associated with significant adverse effects in certain patient populations.
Glossary Term
The goodness of fit statistic for the terminal elimination phase.