Glossary Term

Ligase

PCR TermsEN

Definition

Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by forming a phosphodiester bond.

Extended Notes

Source: National Cancer Institute, NCI Thesaurus 26.09d, C16796. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.

Also Known As

EC 6Ligase
Ligase — IVD Glossary