Glossary Term
Exonuclease
PCR TermsEN
Definition
An Exonuclease is a hydrolase (nuclease) that specifically catalyzes the hydrolysis of terminal phosphodiester bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16242. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Exonuclease
References
- NCI Thesaurus 26.09d — Exonuclease (C16242)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16242. NCI definition, reproduced without modification under CC BY 4.0.
- A fluorescent aptamer-based method for kanamycin detection incorporating G-quadruplex DNAzyme and exonuclease III-assisted signal amplification. — Chem Commun (Camb), 2026-10-02 (PMID 42704348; literature)
- Unlocking the hidden DNAzyme repertoire through aptamer-gated exonuclease signal amplification. — Chem Commun (Camb), 2026-10-02 (PMID 42703810; literature)
- Exonuclease III-Proofread high-fidelity primer exchange reaction enables ultrasensitive analysis of prostate cancer MicroRNA. — Biosens Bioelectron, 2026-10-01 (PMID 42830000; literature)
- Exonuclease-gated CRISPR/Cas12a biosensing strategy for sensitive detection of lncRNA MIR155HG. — J Pharm Biomed Anal, 2026-10-20 (PMID 42950501; literature)