Glossary Term
Any hybrid gene formed from two previously separate genes. Such fusions occur as a result of translocation, intersititial deletion or chromosomal inversion, and often result in gene products with functions different from the two fusion partners. Gene fusions are associated frequently with hematological cancers, sarcomas and prostate cancer.
Pcr Terms
Producto
Molecular Assays
Producto
Molecular Assays
Technology
A technique designed to rapidly enrich and amplify targets derived from samples that yield low levels of nucleic acids, such as formalin-fixed paraffin-embedded (FFPE) tissues, for use in next-generation sequencing. Briefly, total nucleic acid or genomic DNA (gDNA) is isolated from fresh or FFPE tissues. Total nucleic acid is converted to double-stranded cDNA (dscDNA) and cleaned by solid-phase reversible immobilization (SPRI). Then the dscDNA or gDNA is subjected to end repair, adenylation and ligation with a universal half-functional adapter. The modified DNA sample is then subjected to two rounds of nested low-cycle PCR, where the first round uses target gene-specific primers and the second round uses nested target gene-specific primers that are 5' tagged with a common sequencing adapter. The resulting target amplicon library is cleaned using SPRI and is suitable for use in next generation genomic assays.
Diagnostic Methods
Producto
ApoE/SLCO1B1 Gene Polymorphism Detection Kit is catalogued from public product materials published by Tianlong (天隆科技). Availability: not published on this record. Regulatory status is manufacturer-reported and has not been independently verified. Confirm intended use, compatibility and local registration against official documentation before procurement.
Molecular Assays
Company
We are the authorized distributor for world-renowned and innovative suppliers of instruments, reagents and consumables for analytical sciences, clinical diagnostics, food and pharmaceutical safety, life
Distributor
Company
DaAn Gene Co., Ltd. is an IVD supplier based in China, with a source-linked product portfolio. Molecular Assays. Coverage spans Molecular Assays | qPCR | STI.
Manufacturer
Technology
A physical mapping approach that uses fluorescent tags to detect hybridization of probes within metaphase chromosomes or less condensed somatic interphase chromatin. This technique can be used for identification of chromosomal abnormalities and for gene mapping.
Diagnostic Methods
Producto
Molecular Assays
Technology
Analysis using microarray technology (e.g., cDNA arrays to see gene expression or protein microarrays to profile the pattern of proteins).
Diagnostic Methods
Producto
Molecular Assays
Producto
VitaSIRO solo™ MT-RNR1 SNP Assay is catalogued from public product materials published by Credo Diagnostics. Availability: not published on this record. Regulatory status is manufacturer-reported and has not been independently verified. Confirm intended use, compatibility and local registration against official documentation before procurement.
Molecular Assays