National Cancer Institute (source definition)
Whole Genome Amplification
Any technique designed to amplify a limited genomic DNA sample so as to generate a new sample that is indistinguishable from the original but with a higher DNA concentration.
Review and references
Automated source check (NCI definition)
2026-10-20
2026-10-28
professional use
References
- NCI Thesaurus 26.09d — Whole Genome Amplification (C19590)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C19590. NCI definition, reproduced without modification under CC BY 4.0.
- DLMDA pre-amplification preserves genome-wide copy-number profiles in FFPE samples despite reduced detection sensitivity. — Methods, 2026-10-11 (PMID 42860194; literature)
- Direct whole-genome sequencing of Coxiella burnetii from environmental samples using a two-step selective enrichment approach. — PLoS Negl Trop Dis, 2026-09-08 (PMID 42709868; literature)
- Wavelet-based whole genome doubling aware single-cell copy number calling. — Nucleic Acids Res, 2026-09-01 (PMID 42851130; literature)
- Random PCR-based nanopore whole-genome sequencing enables pre-positivity detection of fungal bloodstream infections. — Microbiol Spectr, 2026-08-21 (PMID 42627185; literature)
- Retrospective Whole-Genome Sequencing and Molecular Epidemiological Analysis of Austrian WNV-2 Veterinary Cases (2008-2025). — Pathogens, 2026-10-08 (PMID 42931213; literature)
What it is
Any technique designed to amplify a limited genomic DNA sample so as to generate a new sample that is indistinguishable from the original but with a higher DNA concentration.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C19590. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Explore more
Same category
Tissue Culture Infectious Dose 50%
A potency unit defined as a minimal dose of infectious material at which preparation causes cytopathic effects (changes in the morphology and metabolism of tissue culture cells, indicatin…
Same categoryEpsilometry
A method to determine microbial susceptibility to antibiotics in which a plastic strip impregnated with the antibiotic of interest is placed on an agar plate that has been inoculated with…
Same categoryViral Identification
A diagnostic procedure to identify and characterize a viral organism.