National Cancer Institute (source definition)
Fluorescence In Situ Hybridization
A physical mapping approach that uses fluorescent tags to detect hybridization of probes within metaphase chromosomes or less condensed somatic interphase chromatin. This technique can be used for identification of chromosomal abnormalities and for gene mapping.
Review and references
Automated source check (NCI definition)
2026-10-18
2026-10-27
professional use
References
- NCI Thesaurus 26.09d — Fluorescence In Situ Hybridization (C17563)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C17563. NCI definition, reproduced without modification under CC BY 4.0.
- Fluorescence in situ hybridization reveals endophytic and epiphytic root colonization of the novel plant growth-promoting bacterium Citrobacter sedlakii CESi7. — Biosci Biotechnol Biochem, 2026-10-23 (PMID 42913500; literature)
- Fusion Detection in Microsecretory Adenocarcinoma and Mucoepidermoid Carcinoma Using Chromogenic RNA In Situ Hybridization: A Promising Alternative to DNA-Based Fluorescence In-Situ Hybridization. — Mol Carcinog, 2026-10-25 (PMID 42927643; literature)
What it is
A physical mapping approach that uses fluorescent tags to detect hybridization of probes within metaphase chromosomes or less condensed somatic interphase chromatin. This technique can be used for identification of chromosomal abnormalities and for gene mapping.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C17563. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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