Search IVDmap

Search products, companies, tests, and guides — go from query to quote request in one place.

Glossary Term

Dideoxy Chain Termination DNA Sequencing

A DNA sequencing technique in which a mixture of deoxynucleosidetriphosphates (dNTPs) and chain-terminating dNTPs, which are radioactively or fluorescently labeled, are combined within the reaction mixture. Once the reaction is complete, the DNA strands are separated by size, and the labeled chain terminating dNTPs can be read in sequence by the investigator or by a machine.

Pcr Terms

Indicators

Dihydrotestosterone

The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice.

Article

Disseminated paracoccidioidomycosis in a black lion tamarin (Leontopithecus chrysopygus) confirmed by histopathology, molecular diagnostics and phylogenetic analysis of DNA from FFPE tissues.

Research record from Vet Res Commun, 2026-08-08. PMID 42570048.

Article

Disseminated Strongyloides stercoralis infection diagnosed by metagenomic next-generation sequencing of a cell-free DNA blood sample in a patient with hematologic malignancy in Germany: A case report.

Research record from Int J Infect Dis, 2026-03-30. PMID 41921901.

Glossary Term

DNA

A long linear double-stranded polymer formed from nucleotides attached to a deoxyribose backbone and found in the nucleus of a cell; associated with the transmission of genetic information.

Pcr Terms

Glossary Term

DNA Damage

Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis.

Pcr Terms

Tests