Glossary Term
Allele
Mutually exclusive alternative forms of the same gene occupying the same locus on homologous chromosomes, differing in nucleotide sequence and governing the same biochemical and developmental process.
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Glossary Term
Mutually exclusive alternative forms of the same gene occupying the same locus on homologous chromosomes, differing in nucleotide sequence and governing the same biochemical and developmental process.
Tests
The determination of the amount of alpha globulin present in a sample.
Tests
The determination of the amount of alpha-1 acid glycoprotein present in a sample.
Indicators
Alpha-1-acid glycoprotein 1 (201 aa, ~24 kDa) is encoded by the human ORM1 gene. This protein may play a role in immunosuppression and small molecule transport.
Indicators
Alpha-2-macroglobulin (1474 aa, ~163 kDa) is encoded by the human A2M gene. This protein has activity as a protease inhibitor.
Tests
The determination of the amount of alpha-fetoprotein present in a blood sample.
Tests
The determination of the amount of the alpha-methylfentanyl in a sample.
Tests
The determination of the amount of alpha-N-acetylglucosaminidase present in a sample.
Indicators
The orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.
Glossary Term
Alternate Splicing is a process in which multiple protein isoforms or products are generated from a single gene as a result of splicing together different nonconsecutive exons during the processing of initially identical nascent transcripts of a gene into mature mRNA transcripts. An exon may be connected to any one of several alternative exons to form the mRNA and generate related proteins, often in a tissue or developmental stage specific manner.
Indicators
A metallic element in the boron group with atomic symbol Al, atomic number 13, and atomic weight 27.
Partner
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