Glossary Term
Allele
PCR TermsEN
Definition
Mutually exclusive alternative forms of the same gene occupying the same locus on homologous chromosomes, differing in nucleotide sequence and governing the same biochemical and developmental process.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16277. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
AlleleAlleles
References
- NCI Thesaurus 26.09d — Allele (C16277)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16277. NCI definition, reproduced without modification under CC BY 4.0.
- Clinical relevance of the newly reclassified HLA-C*04:09L low-expression allele in allogeneic hematopoietic cell transplantation: a case report. — Transpl Immunol, 2026-10-15 (PMID 42880374; literature)
- Detecting low-allele-fraction mosaic mutations: A multi-institution benchmarking with cell-line mixtures. — Cell Genom, 2026-10-15 (PMID 42880247; literature)
- HLA allele DRB1*01:03: the genetic link to neutralizing IL-10 antibodies in inflammatory bowel disease. — Signal Transduct Target Ther, 2026-10-27 (PMID 42934236; literature)