Glossary Term
Oligonucleotide Primer
Short DNA oligonucleotide chains used to prime DNA (and in some cases RNA) synthesis.
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Glossary Term
Short DNA oligonucleotide chains used to prime DNA (and in some cases RNA) synthesis.
Indicators
This gene may play a role in the repair of DNA damage that is resolved by recombination.
Tests
Pharmacogenetics (also called pharmacogenomics ) is the study of how your genes affect the way your body responds to certain medicines . Genes are parts of DNA in your cells that you inherit from your parents. You inherit two copies of each gene, one from each parent. Genes carry information that controls what you look like and how your body works.
Glossary Term
A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point mutations.
Indicators
This gene is involved in DNA replication and proofreading.
Indicators
This gene is involved in both DNA replication and DNA base-excision repair.
Glossary Term
General term for a piece of DNA or RNA corresponding to a gene or sequence of interest, that has been labelled either radioactively or with some other detectable molecule, such as biotin, digoxygenin or fluorescein. As stretches of DNA or RNA with complementary sequences will hybridize, a probe will label viral plaques, bacterial colonies or bands on a gel that contain the gene of interest.
Glossary Term
A DNA sequence at which RNA polymerase binds and initiates transcription.
Glossary Term
Nonfunctional DNA sequences that are very similar to the sequences of known genes. Many seem to have arisen as functional gene duplications that subsequently underwent mutation and loss of function. Others are structurally similar to mRNA and seem to have arisen by a reverse transcription event followed by integration into the genome. Some pseudogenes are transcribed and may play a role in regulation of its homologous gene.
Indicators
This gene plays a role in DNA double-strand break repair.
Indicators
This gene is involved in both homologous recombination and repair of DNA.
Indicators
This gene plays a role in DNA repair and meiotic recombination.