Glossary Term
Point Mutation
PCR TermsEN
Definition
A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point mutations.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C62200. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Point Mutation
References
- NCI Thesaurus 26.09d — Point Mutation (C62200)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C62200. NCI definition, reproduced without modification under CC BY 4.0.
- A point mutation in duck plague virus gB enhances viral fusogenicity and intercellular dissemination via SNAP25-mediated membrane fusion. — Poult Sci, 2026-10-07 (PMID 42858563; literature)
- A rapid and straightforward detection of the novel obesity gene LGR4 A750T point mutation by the single-tube Cas12a system with split crRNA. — J Mater Chem B, 2026-09-16 (PMID 42677820; literature)
- Fusarium asiaticum FaSdhC2 Point Mutation A83V Confers Resistance to Pydiflumetofen and Development of a Rapid LAMP Detection Method. — J Agric Food Chem, 2026-10-01 (PMID 42916055; literature)
- A premature ovarian insufficiency-associated LMD-3 point mutation impairs protein stability and causes autophagic-lysosomal dysfunction in Caenorhabditis elegans. — PLoS One, 2026-10-27 (PMID 42945204; literature)