Glossary Term
Probe
PCR TermsEN
Definition
General term for a piece of DNA or RNA corresponding to a gene or sequence of interest, that has been labelled either radioactively or with some other detectable molecule, such as biotin, digoxygenin or fluorescein. As stretches of DNA or RNA with complementary sequences will hybridize, a probe will label viral plaques, bacterial colonies or bands on a gel that contain the gene of interest.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C43523. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Probe
References
- NCI Thesaurus 26.09d — Probe (C43523)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C43523. NCI definition, reproduced without modification under CC BY 4.0.
- Enzyme-Activatable Probe for Tumor Bimodal Imaging, Intraoperative Navigation, and Urinalysis. — Adv Healthc Mater, 2026-10-16 (PMID 42885996; literature)
- A novel double-stranded probe minimizes false-positive and false-negative LAMP results with ultrasensitivity and high specificity. — Analyst, 2026-10-20 (PMID 42899696; literature)
- Boosting Carrier Mobility and Restoring Ambipolarity in 2D TMD Transistors via Nano-spherical Probe Cleaning. — ACS Appl Mater Interfaces, 2026-10-20 (PMID 42896836; literature)
- What the Probe Cannot Show. — Anesthesiology, 2026-10-27 (PMID 42937259; literature)
- Tip-sample distance dependence of local work function in Kelvin probe force microscopy on Pb/Si(111) islands. — Phys Chem Chem Phys, 2026-10-27 (PMID 42937099; literature)