Glossary Term
Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome.
Pcr Terms
Tests
The determination of the amount of HLA class I antibody present in a sample.
For professionals
Tests
The determination of the amount of HLA class IA histocompatibility antigen present in a sample.
For professionals
Tests
The determination of the number of mismatch between the study subject and his or her donor for the human leukocyte antigen, class I, group A (HLA-A).
For professionals
Indicators
This gene plays a role in both immune responses and histocompatibility processes.
Tests
The determination of the number of mismatch between the study subject and his or her donor for the human leukocyte antigen, class I, group B (HLA-B).
For professionals
Tests
The identification of the type of human leukocyte antigen, class II, antigen-D-related 52 (HLA-DR52), in a sample.
For professionals
Tests
The determination of the ratio of IgM positive class-switched memory B-Lymphocytes to class-switched memory B-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Glossary Term
A mutation class that includes insertion mutations, deletion mutations and mutation events where both an insertion and a deletion has occurred.
Pcr Terms
Indicators
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least 13 functional genes and 1 pseudogene.
Indicators
Interleukin-4 (153 aa, ~17 kDa) is encoded by the human IL4 gene. This protein is involved in the regulation of the expression of class II MHC molecules, Fc receptors and cell surface-bound immunoglobulins.
Glossary Term
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by forming a phosphodiester bond.
Pcr Terms
