Indicator Explainer
Interleukin-4
Interleukin-4 (153 aa, ~17 kDa) is encoded by the human IL4 gene. This protein is involved in the regulation of the expression of class II MHC molecules, Fc receptors and cell surface-bound immunoglobulins.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C20508. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
Related Tests
Tests that measure or involve this indicator.
References
- NCI Thesaurus 26.09d — Interleukin-4 (C20508)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C20508. NCI definition, reproduced without modification under CC BY 4.0.
- Interleukin-4 Genetic Polymorphisms Predict Susceptibility to Childhood Acute Lymphoblastic Leukemia. — Anticancer Res, 2026-10-01 (PMID 42823151; literature)
- Hybrid-Fused Extracellular Vesicles from M2 Macrophages and Keratinocytes Attenuate Ultraviolet B-Induced Skin Photoaging via the Interleukin-4 Receptor Alpha/Janus Kinase/Signal Transducer and Activator of Transcription 3-Mediated Pathway. — ACS Appl Mater Interfaces, 2026-10-01 (PMID 42817007; literature)