Indicators
Coagulation Factor XI
Coagulation factor XI (625 aa, ~70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX.
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Indicators
Coagulation factor XI (625 aa, ~70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX.
Indicators
Coagulation factor XII (615 aa, ~68 kDa) is encoded by the human F12 gene. This protein is involved in blood coagulation and fibrinolysis.
Glossary Term
A specific sequence of three adjacent bases on a strand of DNA or RNA that provides genetic code information for a particular amino acid.
Glossary Term
The ratio of standard deviation to mean, expressed as a percentage or fraction.
Glossary Term
A research study that compares a particular outcome (such as lung cancer) in groups of individuals who are alike in many ways but differ by a certain characteristic (for example, female nurses who smoke compared with those who do not smoke).
Tests
The determination of the amount of complement Bb present in a sample.
Indicators
Complement C2 (752 aa, ~83 kDa) is encoded by the human C2 gene. This protein is involved in post-translational protein processing and complement activity.
Tests
The determination of the amount of the complement C3c in a sample.
Indicators
Complement C5 (1676 aa, ~188 kDa) is encoded by the human C5 gene. This protein is involved in complement-mediated immunity.
Tests
The determination of the amount of complement C5b-9 present in a sample.
Indicators
A protein complex composed of 18 complement component 1q (C1q) subcomponent chains: six C1qA, six C1qB and six C1qC. The C1q complex is part of the complement component C1 complex (C1 complex) and undergoes confirmational rearrangement following binding of pentraxins or antigen-antibody complexes that include either immunoglobulin M (IgM) or several IgG molecules. These confirmational changes activate the C1r chains of the C1 complex, which, in turn, cleaves C1s chains of the C1 complex. Following C1s cleavage, the C1 complex can proteolytically activate C2 and C4 and promotes formation of C3-convertase, which cleaves C3 and activates the classical complement pathway.
Indicators
Complement component C6 (934 aa, ~105 kDa) is encoded by the human C6 gene. This protein is involved in complement-mediated host defense responses.