Indicator Explainer
Complement C2
Complement C2 (752 aa, ~83 kDa) is encoded by the human C2 gene. This protein is involved in post-translational protein processing and complement activity.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C126958. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Complement C2 (C126958)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C126958. NCI definition, reproduced without modification under CC BY 4.0.
- In Vivo Efficacy of an Inhibitor of Complement and FcRn in Models of Glomerulonephritis and Collagen-Induced Arthritis Using Human C2 Knock-In Mice. — Int J Mol Sci, 2026-06-18 (PMID 42353239; literature)
- Structure-function analysis of empasiprubart, a calcium- and pH-dependent clinical phase complement C2 blocking antibody. — MAbs, 2026-05-04 (PMID 42080322; literature)
- CSL305: A Dual Functional Therapeutic Antibody Targeting Complement C2 and FcRn. — Int J Mol Sci, 2026-03-04 (PMID 41828601; literature)
- Development of an anti-rat complement C2 antibody that improves renal outcome in a rat kidney transplant model. — Front Immunol, 2026-01-15 (PMID 41624835; literature)