Indicator Explainer
von Willebrand Factor
von Willebrand factor (2813 aa, ~309 kDa) is encoded by the human VWF gene. This protein is involved in platelet adhesion and blood coagulation.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16572. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — von Willebrand Factor (C16572)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16572. NCI definition, reproduced without modification under CC BY 4.0.
- The Contribution of Bleeding Assessment Score and Pictorial Blood Loss Assessment Chart to the Diagnosis of Von Willebrand Disease in Adolescent Girls With Iron Deficiency Anemia. — J Pediatr Hematol Oncol, 2026-10-08 (PMID 42848004; literature)
- Beyond endothelial cells: mutant p53 drives de novo von Willebrand factor expression. — J Thromb Haemost, 2026-10-01 (PMID 42816008; literature)
- Von Willebrand Factor Biomarkers in Prosthetic Valve Dysfunction: An Adjunct to Imaging and Hemodynamic Assessment. — Cardiol Rev, 2026-10-15 (PMID 42875881; literature)
- Small interfering RNA targeting protein Z-dependent protease inhibitor improves hemostasis in Von Willebrand factor- and Factor X-deficient mice. — Thromb Haemost, 2026-10-14 (PMID 42874635; literature)
- 100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD. — Haemophilia, 2026-10-12 (PMID 42864839; literature)
- Cost comparison of pdVWF/FVIII prophylaxis and on-demand therapy in type 3 von Willebrand disease in the United States. — Blood Adv, 2026-10-01 (PMID 42431629; literature)
- von Willebrand Factor and ADAMTS13 Predict Therapeutic Efficacy and Severe Adverse Events in Advanced Hepatocellular Carcinoma Treated With Atezolizumab-Bevacizumab. — JGH Open, 2026-10-27 (PMID 42948561; literature)
- Type 2M von Willebrand Disease Mutations Impair Platelet Adhesion Through Distinct Effects Involving Enhanced A1/A2 Interactions. — J Thromb Haemost, 2026-10-23 (PMID 42918501; literature)