Indicator Explainer
Transthyretin
Transthyretin (147 aa, ~16 kDa) is encoded by the human TTR gene. This protein is involved in both the binding and transport of retinol and thyroxine.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C79964. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
Related Tests
Tests that measure or involve this indicator.
References
- NCI Thesaurus 26.09d — Transthyretin (C79964)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C79964. NCI definition, reproduced without modification under CC BY 4.0.
- Myocardial work in light-chain and transthyretin-related amyloidosis with preserved ejection fraction: a cardiovascular magnetic resonance study. — Insights Imaging, 2026-10-09 (PMID 42855647; literature)
- Do Extracellular Vesicles and the Biochemical Microenvironment Contribute to Amyloid Transthyretin Cardiomyopathy? — JACC Adv, 2026-10-09 (PMID 42854598; literature)
- Disease-Modifying Therapy Uptake in Transthyretin Amyloid Cardiomyopathy: A 10-Year US Analysis of 77,000 Patients Across Three Approved Agents. — J Nucl Cardiol, 2026-10-14 (PMID 42874836; literature)
- Machine Learning of Echocardiographic Left Ventricular Myocardial Radiomics for Identification of Transthyretin Amyloid Cardiomyopathy. — JACC Adv, 2026-10-13 (PMID 42868962; literature)
- Molecular Identification of Transthyretin Amyloid in Fixed Skin Biopsies: A Simplified Sample Preparation Method. — J Vis Exp, 2026-10-16 (PMID 42891599; literature)
- Disease progression in transthyretin cardiac amyloidosis treated with disease-modifying therapies: a multicenter real-world experience. — Med Clin (Barc), 2026-10-16 (PMID 42887471; literature)
- Prevalence and prognostic impact of valvular heart disease in transthyretin cardiac amyloidosis. — Amyloid, 2026-10-29 (PMID 42954412; literature)
- Towards the diagnostic scores we need in ATTR-CM: Editorial for the article: Comparison of three scoring systems in the identification of transthyretin cardiac amyloidosis in a HFpEF cohort. — Int J Cardiol, 2026-10-27 (PMID 42946136; literature)