Glossary Term
Chromatin
PCR TermsEN
Definition
The genetic material of the nucleus, consisting of deoxyribonucleoprotein, which occurs in two forms during the phase between mitotic divisions: 1) as heterochromatin, seen as condensed, readily stainable clumps; 2) as euchromatin, dispersed lightly staining or nonstaining material. During mitotic division the chromatin condenses into chromosomes.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C13201. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Chromatin
References
- NCI Thesaurus 26.09d — Chromatin (C13201)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C13201. NCI definition, reproduced without modification under CC BY 4.0.
- Electrostatic control of chromatin compaction safeguards against apoptotic DNA release. — EMBO J, 2026-10-16 (PMID 42888264; literature)
- The trifecta of Plasmodium falciparum chromatin: open, closed, and centric. — Trends Parasitol, 2026-10-16 (PMID 42888052; literature)
- The role of gene regulatory evolution in weapon diversification: Insights from comparative genomics, chromatin profiling, and functional analyses of BMP signaling in horned beetles. — PLoS Genet, 2026-10-21 (PMID 42905772; literature)
- BATF condensation drives gastric cancer metastasis via chromatin association and transcriptional regulation. — Cell Rep, 2026-10-21 (PMID 42905520; literature)
- Chromatin rewiring in endothelial cells upon cohesin reduction redistributes genome-wide FLI1 binding. — Epigenetics, 2026-10-23 (PMID 42925159; literature)
- SMCHD1 loss rewires MYOD1 enhancer nexuses and chromatin accessibility landscapes in muscle cells. — Sci Adv, 2026-10-23 (PMID 42912981; literature)
- Genetic variants shape single-cell chromatin accessibility and disease risk. — Nature, 2026-10-28 (PMID 42951970; literature)
- SWI/SNF complexes shape 3D chromatin architecture through CTCF and cohesin. — Nature, 2026-10-28 (PMID 42951962; literature)