Glossary Term
Chromosome
PCR TermsEN
Definition
A structure found in cells that is comprised of a strand of linearized double-stranded DNA plus proteins that package the DNA in a condensed coil form and regulate chromosomal function.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C13202. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
ChromosomalChromosome
References
- NCI Thesaurus 26.09d — Chromosome (C13202)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C13202. NCI definition, reproduced without modification under CC BY 4.0.
- Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends. — Elife, 2026-10-16 (PMID 42885671; literature)
- From genome editing to chromosome engineering in plants. — Trends Biotechnol, 2026-10-20 (PMID 42901830; literature)
- PLD1-driven oncogenic secretion creates a therapeutic vulnerability in chromosome 3q-amplified NSCLC. — Proc Natl Acad Sci U S A, 2026-10-20 (PMID 42900736; literature)
- Correction to: Real-world outcomes of ponatinib in heavily pretreated patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. — Ann Hematol, 2026-10-24 (PMID 42925414; literature)
- Clinical manifestations of Armfield syndrome in females with heterozygous FAM50A variants and skewed X-chromosome inactivation. — Neurol Sci, 2026-10-24 (PMID 42920011; literature)
- Delayed cerebral myelination in a patient with isodicentric chromosome 18 [psu idic(18)(q21.2)] mosaicism: a case report. — Brain Dev, 2026-10-25 (PMID 42927705; literature)
- A Robust Protocol for Germ Layer Differentiation of Human Pluripotent Stem Cells and Evaluation of Their Chromosome and Genomic Integrity. — J Vis Exp, 2026-10-23 (PMID 42921815; literature)
- Synthetic collinearization of a chromosome segment enables genetic dissection of incompatibility between distant genera. — Genetics, 2026-10-28 (PMID 42950127; literature)
- STRIDE: A Sequencing Depth Robust Metric for Sparse Chromosome Conformation Capture Data Comparison. — Adv Sci (Weinh), 2026-10-28 (PMID 42949804; literature)