Glossary Term

Unique Molecular Identifier

Short random nucleotide sequences that are ligated to each primer molecule during amplification of a nucleotide sample during library preparation to act as a unique tag. Their use helps to identify PCR duplicates in sequencing data.

Producto

KAPA Unique Dual-Indexed Adapter Kit

Artículo

An Ultra-High performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of etomidate, analogues, and metabolites in human nail: Unveiling a unique accumulation profile.

Research record from Forensic Toxicol, 2026-06-19. PMID 42319706.

Artículo

Comment on: 'Metagenomic next-generation sequencing: a game changer in the diagnosis of unique intraocular infections'.

Research record from Eye (Lond), 2026-04-08. PMID 41951791.

Artículo

Comprehensive immune profiling of human peripheral blood mononuclear cells using two complementary spectral flow cytometry panels encompassing 60 unique markers.

Research record from Front Immunol, 2026-09-01. PMID 42745795.

Artículo

Extramedullary T-Lymphoblastic Blast Crisis in Chronic Myeloid Leukaemia: A Unique Cytologic Diagnosis Confirmed by Flow Cytometry.

Research record from Cytopathology, 2026-09-07. PMID 42706638.

Glossary Term

Homologous Recombination

The process of exchange of genetic material between autonomous replicons, which depends on regions of extensive sequence homology between the participating DNA strands. This process involves double-strand breakage of one participant, resection of the break, and strand invasion, followed by formation, displacement and resolution of the Holliday junction. This process is involved in repairing broken DNA and creating combinations of genes that may be unique from the parent duplexes. Disruptions in this process can result in inviability, premature aging and predisposition to cancers and degenerative diseases.

Indicadores

IgE

An immunoglobulin isotype (subclass). This isotype has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast cells and basophils and induce degranulation and cytokine production by these cells when they are crosslinked by antigen. In addition to a central role in atopy and allergic responses, it has been speculated that IgE-mediated mast cell degranulation, by its release of mediators that increase vascular permeability, has an important role in the initiation of immune response in general.

Artículo

Response to: 'Comment on 'Metagenomic next-generation sequencing: a game changer in the diagnosis of unique intraocular infections''.

Research record from Eye (Lond), 2026-03-27. PMID 41896456.