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Research record from Int J Parasitol, 2026-06-03. PMID 42242343.
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Lyme disease is an infection caused by bacteria you get from tick bites . Lyme disease tests look for signs of infection in a sample of your blood or cerebrospinal fluid (CSF). CSF is a clear liquid that flows in and around your brain and spinal cord. The test checks your sample for antibodies that your immune system makes to fight the bacteria that cause Lyme disease.