Technology
Methylation Analysis
An analysis of DNA or protein to detect the presence and/or location of methyl groups.
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Technology
An analysis of DNA or protein to detect the presence and/or location of methyl groups.
Glossary Term
The covalent chemical or biochemical addition of a methyl group(s) to a compound. (NCI)
Artículo
Research record from Int J Mol Sci, 2026-02-27. PMID 41828470.
Artículo
Research record from Biosens Bioelectron, 2026-09-25. PMID 42801800.
Artículo
Research record from Int J Legal Med, 2026-04-21. PMID 42010010.
Artículo
Research record from J Mol Diagn, 2026-07-21. PMID 42480851.
Indicadores
This gene is involved in the modulation of histone methylation.
Indicadores
This gene plays a role in both methylation and transcriptional regulation
Indicadores
This gene is involved in epigenetic control of gene expression through histone methylation.
Indicadores
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05)
Indicadores
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.