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One of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active against herpes simplex viruses and present in many forms of diet supplements. The mechanism underlying this effect is based on the viral need for amino acid arginine; lysine competes with arginine for absorption and entry into cells. Lysine inhibits HSV growth by knocking out arginine. (NCI04)
Glossary Term
Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome.
Pcr Terms
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This gene is involved in histone modification.
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This gene is involved in the modulation of histone methylation.
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This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia.
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This gene plays a role in both methylation and transcriptional regulation
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This gene plays a role in co-activation of gene expression.
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This gene is involved in epigenetic control of gene expression through histone methylation.
