Pruebas
Cytochrome P450 2C9 Activity Measurement
The determination of the amount of the biological activity of cytochrome P450 2C9 in a sample.
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Pruebas
The determination of the amount of the biological activity of cytochrome P450 2C9 in a sample.
Artículo
Research record from Int J Parasitol, 2026-06-03. PMID 42242343.
Indicadores
A cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c and caspases 8 and 3. (NCI04)