Pruebas
Carbohydrate-Deficient Transferrin Measurement
The determination of the amount of transferrin with a reduced number of carbohydrate moieties present in a biological sample.
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Pruebas
The determination of the amount of transferrin with a reduced number of carbohydrate moieties present in a biological sample.
Technology
An electrophoresis procedure, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.
Glossary Term
A volatile liquid prepared by fermentation of certain carbohydrates. Alcohol acts as a central nervous system (CNS) depressant, a diuretic, and a disinfectant. Although the exact mechanism of CNS depression is unknown, alcohol may act by inhibiting the opening of calcium channels, mediated by the binding of the inhibitory neurotransmitter gamma-amino butyric acid (GABA) to GABA-A receptors, or through inhibitory actions at N-methyl-D-aspartate (NMDA)-type glutamate receptors. Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. This agent kills organisms by denaturing their proteins.
Pruebas
An amylase test measures the amount of amylase in your blood or urine (pee). Amylase is an enzyme, a protein that speeds up chemical reactions in your body. Amylase helps you digest carbohydrates . Most of the amylase in your body is made by your pancreas and salivary (spit) glands.
Pruebas
A CA 19-9 test measures the amount of a protein called CA 19-9 (cancer antigen 19-9) in a sample of your blood. CA 19-9 is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer .
Indicadores
An antigen expressed by tissues derived from mullerian epithelium (tubal, endometrial and endocervical) or celomic epithelium (mesothelial cells of the pleura, pericardium and peritoneum). Although its biochemical nature has not been clearly defined, CA125 has been described as a glycosylated, high-molecular-weight protein that may be released from damaged cells. Measurable in plasma, CA125 is a sensitive, nonspecific tumor marker for ovarian cancer; as such it is much more useful for monitoring clinical responses to the treatment of ovarian cancer than for the diagnosis of ovarian cancer. Elevated plasma CA125 may occur in association with other malignancies and non-malignant gynecologic disorders. (NCI04)
Indicadores
CA 19-9 is a fucosylated glycosphingolipid carbohydrate antigen that is soluble and is adsorbed to erythrocytes and to many adenocarcinomas of the digestive tract, especially pancreatic tumors. By structure CA 19-9 is related to the Lewis blood group antigens.
Pruebas
The determination of the amount of cancer antigen 19-9 present in a sample.
Pruebas
The determination of the ratio of carbohydrate-deficient transferrin to total transferrin present in a sample. The measurement may be expressed as a ratio or percentage.
Indicadores
Galectin-3 (250 aa, ~26 kDa) is encoded by the human LGALS3 gene. This protein plays a role in both antibody-mediated immunity and carbohydrate binding.
Glossary Term
The covalent chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, by glycosyl transferases.
Indicadores
This gene plays a role in carbohydrate metabolism.