Indicadores
AXIN2 Gene
This gene is involved in signal transduction and plays a role in development.
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Indicadores
This gene is involved in signal transduction and plays a role in development.
Indicadores
This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
Indicadores
This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
Indicadores
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicadores
This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.
Indicadores
This gene plays a role in the repression of gene transcription.
Pruebas
A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1. This abnormal gene is found in certain types of blood cancer , such as chronic myeloid leukemia (CML).
Indicadores
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Indicadores
Beta-2-glycoprotein 1 (345 aa, ~38 kDa) is encoded by the human APOH gene. This protein is involved in binding to phospholipids, glycosaminoglycans and other negatively charged substances.
Artículo
Research record from Cureus, 2026-08-31. PMID 42819076.
Indicadores
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
Indicadores
This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.