Indicadores
GATA3 Gene
This gene plays a role in the modulation of transcription.
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Indicadores
This gene plays a role in the modulation of transcription.
Indicadores
This gene plays a role in both DNA binding and transcriptional modulation.
Indicadores
Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed of a 35-kD IL12A subunit (IL-6 Superfamily) and a 40-kDa IL12B subunit (Type I Cytokine Receptor 3 Family). IL12 stimulates T-cell-independent production of IFN-gamma by PBMCs, enhances NK cell lytic activity, acts as a growth factor for T- and NK-cells, and is important for Th1 and Th2 cell differentiation. Lymphocyte responses to IL12 require NOS2A and are mediated by STAT4 activator of transcription. (NCI)
Indicadores
This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia.
Indicadores
This gene plays a role in both methylation and transcriptional regulation
Indicadores
This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation.
Indicadores
This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
Indicadores
This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
Indicadores
This gene is involved in transcriptional regulation and has tumor suppressor activity.
Indicadores
This gene is involved in transcriptional promotion in melanocytes.
Indicadores
This gene is involved in transcriptional regulation and is frequently amplified in small-cell lung cancer.
Indicadores
This gene is involved in transcriptional regulation and amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.