Indicadores
Anti-Histidine-tRNA Ligase, Cytoplasmic Autoantibody
An autoantibody that recognizes histidyl-tRNA synthetase, cytoplasmic protein.
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Indicadores
An autoantibody that recognizes histidyl-tRNA synthetase, cytoplasmic protein.
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An antinuclear antibody directed against a 47 kDa RNA-binding protein in the nucleus. They can be associated with Sjogren syndrome and system lupus erythematosus. Maternal anti-La antibody positivity can be associated with neonatal lupus.
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An antinuclear antibody directed against 52 or 60 kDa RNA-binding proteins in the nucleus. They can be associated with multiple autoimmune disorders, primarily Sjogren syndrome and system lupus erythematosus. Maternal anti-Ro antibody positivity can be associated with neonatal lupus.
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Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation.
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Apolipoprotein A-I (267 aa, ~31 kDa) is encoded by the human APOA1 gene. This protein is involved in the transport and metabolism of cholesterol.
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Appetite-regulating hormone (117 aa, ~13 kDa) is encoded by the human GHRL gene. This protein is involved in satiety, thirst and anxiety and regulating growth hormone release.
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An essential amino acid in juvenile humans, Arginine is a complex amino acid, often found at active site in proteins and enzymes due to its amine-containing side chain. Arginine may prevent or treat heart and circulatory diseases, combat fatigue, and stimulate the immune system. It also boosts production of nitric oxide, relaxing blood vessels, and treating angina and other cardiovascular problems. Arginine is also an important intermediate in the urea cycle and in detoxification of nitrogenous wastes. (NCI04)
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A naturally occurring allotropic pnictogen and metalloid trace element with atomic symbol As, atomic number 33, and atomic weight 74.92 that is found in water, air, food, and soil, and has a role as a micronutrient. Arsenic, which is highly toxic with acute or chronic exposure to moderate or high levels through an unknown mechanism of action, is used in many industrial processes, as well as in pharmaceuticals, feed additives, and pesticides. It is characterized as a white, yellow, gray metallic, or black solid that is odorless. Exposure occurs by inhalation, ingestion, or contact.
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This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
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A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
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Beta-2-glycoprotein 1 (345 aa, ~38 kDa) is encoded by the human APOH gene. This protein is involved in binding to phospholipids, glycosaminoglycans and other negatively charged substances.
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Beta-2-microglobulin protein (119 aa, ~14 kDa) is encoded by the human B2M gene. This protein plays a role in immune responses and is a key component of major histocompatibility complex class I molecules. The protein is localized to the surface of cells and is utilized as a prognostic marker in persons with cancers that involve white blood cells. The polypeptide is also used as a marker in kidney damage diagnosis and in the detection of viral infection.