Indicadores
MAX Gene
This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
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Indicadores
This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
Indicadores
This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.
Indicadores
One of nine essential amino acids in humans (provided by food), Methionine is required for growth and tissue repair. A sulphur-containing amino acid, methionine improves the tone and pliability of skin, hair, and strengthens nails. Involved in many detoxifying processes, sulphur provided by methionine protects cells from pollutants, slows cell aging, and is essential for absorption and bio-availability of selenium and zinc. Methionine chelates heavy metals, such as lead and mercury, aiding their excretion. It also acts as a lipotropic agent and prevents excess fat buildup in the liver. (NCI04)
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Myoglobin (154 aa, ~17 kDa) is encoded by the human MB gene. This protein is involved in cellular storage and transport of oxygen.
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Neutrophil gelatinase-associated lipocalin (198 aa, ~23 kDa) is encoded by the human LCN2 gene. This protein may play a role in iron transport, apoptosis, and innate immunity.
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A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.
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A peptide released when the heart is under pressure or strain; used in the workup of heart failure.
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Osteocalcin (100 aa, ~11 kDa) is encoded by the human BGLAP gene. This protein is involved in bone development.
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Osteopontin (314 aa, ~35 kDa) is encoded by the human SPP1 gene. This protein is involved in the regulation of both tissue mineralization and cell-cell signaling.
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A water-soluble vitamin ubiquitously found in plants and animal tissues with antioxidant property. Vitamin B5 is a component of coenzyme A (CoA) and a part of the vitamin B2 complex. Vitamin B5 is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids. This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.
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Parathyroid hormone (115 aa, ~13 kDa) is encoded by the human PTH gene. This protein is involved in the modulation of calcium ion and phosphate concentration in the blood.
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A long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A receptor, thereby mimicking the inhibitory actions of GABA in the brain. The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability. In addition, this agent inhibits glutamate induced depolarization.