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Glossary Term
A 50-150bp DNA sequence that increases the rate of transcription of coding sequences. It may be located at various distances and in either orientation upstream from, downstream from or within a structural gene. When bound by a specific transcription factor it increases the levels of expression of the gene, but is not sufficient alone to cause expression. Distinguished from a promoter, that is alone sufficient to cause expression of the gene when bound.
Indicadores
This gene plays a role in DNA repair and regulation of transcription.
Indicadores
This gene is involved in calcium-independent cellular adhesion and in the regulation of immune responses.
Glossary Term
Changes in the regulation of the expression of gene activity without alteration of genetic structure.
Indicadores
This gene plays a role in cellular proliferation and is involved in the oncogenic process through amplification and/or overexpression in several cancers.
Indicadores
This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated with numerous cancers.
Indicadores
This gene is involved in neuronal development and plays a role in receptor tyrosine kinase signal transduction that regulates cellular proliferation and differentiation.
Indicadores
This gene is involved in nucleotide excision repair and corrects sensitivity to UV radiation and defective nucleotide excision repair in xeroderma pigmentosum cells of complementation group D.
Indicadores
This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.
Indicadores
This gene is involved in ligand-activated transcriptional activity.
Indicadores
This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
Glossary Term
The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene.
