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Platelets, also known as thrombocytes, are small blood cells. They form in your bone marrow, the sponge-like tissue in your bones. Platelets are essential for blood clotting . A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. When you get hurt, your body forms a blood clot to stop the bleeding.
Indicators
Platelet-activating factor acetylhydrolase (441 aa, ~50 kDa) is encoded by the human PLA2G7 gene. This protein is involved in platelet-activating factor metabolism.
Tests
A pleural fluid analysis is a group of tests that examine a sample of abnormal fluid that builds up in the space between your lungs and chest wall. This space is called the pleural space.
Indicators
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 3.
Glossary Term
A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point mutations.
Glossary Term
A distribution function used to describe the occurrence of rare events or to describe the sampling distribution of isolated counts in a continuum of time or space. This special probability distribution can apply to the number of discrete independent random events occurring in a given interval when knowing their average rate of occurrence over a very long interval.
Indicators
This gene is involved in DNA replication and proofreading.
Indicators
This gene is involved in both DNA replication and DNA base-excision repair.
Glossary Term
Encoded by Polymerase Genes, Polymerase enzymes catalyze polymerization reactions, especially of nucleotides to polynucleotides. (NCI)
Tests
Porphyrin tests measure the level of porphyrins in your blood, urine (pee), or stool (poop). Your body uses porphyrins to make heme. Heme is part of hemoglobin, which is a protein in your red blood cells that carries oxygen from your lungs to the rest of your body.
Glossary Term
A control sample that is known to produce a positive result if the test is working as expected.
Glossary Term
The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation.
