Glossary Term
Restriction Endonuclease
Enzymes that exhibit endonuclease activity at a specific short nucleotide sequence to cleave strands of DNA.
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Glossary Term
Enzymes that exhibit endonuclease activity at a specific short nucleotide sequence to cleave strands of DNA.
Glossary Term
A sequence in DNA that can be recognized by a specific restriction enzyme.
Glossary Term
An RNA-dependent DNA polymerase that is involved in the replication of retroviruses an in the maintenance of telomeres.
Glossary Term
A two-step setup in which RNA is first copied into complementary DNA by a reverse transcriptase and then amplified by PCR. Used for RNA viruses such as influenza, RSV, SARS-CoV-2, and HCV. In procurement documents, confirm whether "RT-PCR" refers to real-time (quantitative) or endpoint (qualitative) reading.
Glossary Term
The action of copying RNA into DNA by reverse transcriptase.
Glossary Term
Single-stranded long chain of nucleotides containing ribose. It is the end product of DNA transcription by the enzyme RNA polymerase. It is essential in protein synthesis.
Tests
The determination of the amount of DNA from any member of the genus Rickettsia in a sample.
Tests
The determination of the amount of DNA from any member of the genus Salmonella in a biological sample.
Indicators
An anti-nuclear autoantibody that recognizes a 70 kDa fragment of DNA topoisomerase 1. It is associated with scleroderma.
Article
Research record from Toxicon, 2026-09-28. PMID 42805463.
Article
Research record from Anal Chim Acta, 2026-05-05. PMID 42191257.
Glossary Term
A collection of double stranded DNA fragments flanked by oligonucleotide sequence adapters to enable their analysis by high-throughput sequencing.