Glossary Term
Reverse Transcriptase
PCR TermsEN
Definition
An RNA-dependent DNA polymerase that is involved in the replication of retroviruses an in the maintenance of telomeres.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C17096. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
EC 2.7.7.49Reverse TranscriptaseRNA-Dependent DNA Polymerase
References
- NCI Thesaurus 26.09d — Reverse Transcriptase (C17096)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C17096. NCI definition, reproduced without modification under CC BY 4.0.
- Precise detection of telomerase reverse transcriptase C228T mutation using label-free and magnetically induced self-assembly electrochemical biosensors. — Bioelectrochemistry, 2026-10-19 (PMID 42893892; literature)
- Residues E124, K129, and R134 in eEF1A domain I promote ALV-J replication via association with reverse transcriptase. — J Virol, 2026-10-23 (PMID 42925039; literature)